CancerTYPE ID® publications and scientific presentations

Analytical Validity
Clinical Validity
Clinical Utility
Health Economics
Review Documents

Analytical Validity

Blinded Comparator Study of Immunohistochemical Analysis versus a 92-Gene Cancer Classifier in the Diagnosis of the Primary Site in Metastatic Tumors
Lawrence M. Weiss, Peiguo Chu, Brock E. Schroeder, Veena Singh, Yi Zhang, Mark G. Erlander, and Catherine A. Schnabel. J Mol Diagn 2013 March 2013, Vol. 15, No. 2. 263-269.

Performance and Clinical Evaluation of the 92-Gene Real-Time PCR Assay for Tumor Classification.
Mark G. Erlander, Xiao-Jun Ma, Nicole C Kesty, Lei Bao, Ranelle Salunga, Catherine A. Schnabel. J Mol Diagn 2011 September 2011, Vol. 13, No. 5. 492-503.

Molecular Classification of Human Cancers Using a 92-Gene Real-Time Quantitative Polymerase Chain Reaction Assay
Ma, XJ et. al. Archives of Pathology & Laboratory Medicine. April 2006, Vol. 130, No. 4. 465-473.

Molecular Classification of Tumor of Unknown Origin by Gene-Expression from Fixed Paraffin Embedded Tissue
Erlander, MG et al. American Society of Clinical Oncology, June 2004.

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Clinical Validity

Blinded Comparator Study of Immunohistochemical Analysis versus a 92-Gene Cancer Classifier in the Diagnosis of the Primary Site in Metastatic Tumors
Lawrence M. Weiss, Peiguo Chu, Brock E. Schroeder, Veena Singh, Yi Zhang, Mark G. Erlander, and Catherine A. Schnabel. J Mol Diagn 2013 March 2013, Vol. 15, No. 2. 263-269.

Multisite Validation Study to Determine Performance Characteristics of a 92-Gene Molecular Cancer Classifier
Kerr, SE et al. Clinical Cancer Research. May 2012.

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Performance and Clinical Evaluation of the 92-Gene Real-Time PCR Assay for Tumor Classification.
Erlander, MG et al. Journal of  Molecular Diagnostics. September 2011, Vol. 13, No. 5. 492-503.

Molecular Profiling in Unknown Primary Cancer: Accuracy of Tissue of Origin Prediction
Greco, FA et al. The Oncologist. 2010;15:500-506.

Unknown Primary Cancer (UPC): Accuracy of Tissue of Origin Prediction by Molecular Profiling
Greco, FA et al. American Society of Clinical Oncology Annual Meeting Poster Presentation. May/June, 2009.

Molecular Classification of Human Cancers Using a 92-Gene Real-Time Quantitative Polymerase Chain Reaction Assay
Ma, XJ et. al. Archives of Pathology & Laboratory Medicine. April 2006, Vol. 130, No. 4. 465-473.

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Clinical Utility

Molecular Gene Expression Profiling to Predict the Tissue of Origin and Direct Site-Specific Therapy in Patients With Carcinoma of Unknown Primary Site: A Prospective Trial of the Sarah Cannon Research Institute
Hainsworth, JD et al. Journal of Clinical Oncology, October 2012

Multisite Validation Study to Determine Performance Characteristics of a 92-Gene Molecular Cancer Classifier
Kerr, SE et al. Clinical Cancer Research. May 2012.

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A Retrospective Study of Treatment Outcomes in Patients with Carcinoma of Unknown Primary Site and a Colorectal Cancer Molecular Profile
Hainsworth, JD et al. Clinical Colorectal Cancer. 2011 (10.1016/j.clcc.2011.08.001).

Diagnostic utility of molecular profiling for cancers of uncertain primary.
Laouri, M. et al. Journal of Clinical Oncology. 2011; Vol. 29 (suppl; abstr e21103).

Molecular tumor classification using a 92-gene assay in the differential diagnosis of squamous cell lung cancer
McGee R, et al. Community Oncol. 2011; 8:123-131.

Molecular Profiling in Unknown Primary Cancer: Accuracy of Tissue of Origin Prediction
Greco, FA et al. The Oncologist. 2010;15:500-506.

Evolving Understanding and Current Management of Patients with Cancer of Unknown Primary Site
Greco, FA. Commun Oncol. 2010; 7:183-188.

Treatment of Carcinoma of Unknown Primary Site (CUP) Directed by Molecular Profiling Diagnosis: A Prospective, Phase II Trial
Hainsworth, JD et al. American Society of Clinical Oncology Annual Meeting Poster Presentation, June, 2010.

Unknown Primary Cancer (UPC): Accuracy of Tissue of Origin Prediction by Molecular Profiling
Greco, FA et al. American Society of Clinical Oncology Annual Meeting Poster Presentation, May/June, 2009.

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Health Economics

Psychosocial Aspects of Treating Patients with Cancer of Unknown Primary (CUP): A Survey of Oncology Social Workers
McCormick, BK; Erlander, MG. Association of Oncology Social Work Annual Conference Poster Presentation, May, 2009.

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Review Documents

Molecular Classification of Cancers of Unknown Primary Site
Greco, FA; Erlander, MG. Mol Diagn Ther. 2009 Dec 1;13(6):367-73.

Molecular Classification of Unknown Primary Cancer
Bender, RA; Erlander, MG. Sem Oncol. 2009;36:38-43.

Gene-Expression Profiling and Cancer of an Unknown Primary Origin
Acevedo, P; Castro, V. Commun Oncol. 2008;5:590-592.

Molecular Classification of Cancer: Implications for Carcinoma of Unknown Primary
Erlander, MG. United States and Canadian Academy of Pathology meeting, AMP companion meeting, March 25, 2007.

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